Charles River Labs /US

ISIN US1598641074

WKN 939391

Market cap (in EUR)

12,080 m

Country

United States

Sector

Healthcare

Dividend yield

0.00%

Overview

Quote

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Description

Charles River Laboratories International, Inc. engages in providing products and services to help pharmaceutical and biotechnology companies. It operates through the following segments: Research Models and Services (RMS), Discovery and Safety Assessment (DSA), and Manufacturing Solutions. The Research Models and Services segment includes its insourcing solutions business and Charles River accelerator and development lab footprint. The Discovery and Safety Assessment segment offers regulatory-required safety testing of potential new drugs, vaccines, industrial and agricultural chemicals, consumer products, veterinary medicines, and medical devices. The Manufacturing Solutions segment focuses on microbial solutions and biologics solutions. The company was founded by Henry L. Foster in 1947 and is headquartered in Wilmington, MA.

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Healthcare Healthcare Services Outsourced Development and Manufacturing Services United States

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Financials

Key metrics

Market capitalisation, EUR	12,080 m
EPS, EUR	-4.16
P/B ratio	5.0
P/E ratio	578.8
Dividend yield	0.00%

Income statement (2025)

Revenue, EUR	3,559 m
Net income, EUR	-128 m
Profit margin	-3.59%

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Capital at risk

What ETF is Charles River Labs /US in?

There are 161 ETFs which contain Charles River Labs /US. All of these ETFs are listed in the table below. The ETF with the largest weighting of Charles River Labs /US is the Franklin ClearBridge US Smaller Companies UCITS ETF Acc.

ETF	Weight	Investment focus	Fund size (in m EUR)
Amundi MSCI World Small Cap ESG Broad Transition UCITS ETF Acc	0.16%	Equity World Small Cap Climate Change	484
UBS MSCI USA Select Factor Mix UCITS ETF hEUR acc	0.04%	Equity United States Multi-Factor Strategy	8
UBS S&P 500 Scored & Screened UCITS ETF hCHF acc	0.03%	Equity United States Social/Environmental	393
Xtrackers S&P 500 Swap UCITS ETF 1C	0.02%	Equity United States	3,885
Xtrackers MSCI World Small Cap UCITS ETF 1D	0.13%	Equity World Small Cap	15
Xtrackers S&P 500 Equal Weight UCITS ETF 1C	0.29%	Equity United States Equal Weighted	11,398
iShares S&P 500 Swap UCITS ETF EUR Hedged (Acc)	0.02%	Equity United States	675
iShares S&P 500 Swap UCITS ETF USD (Acc)	0.02%	Equity United States	14,174
Invesco Global Buyback Achievers UCITS ETF	0.23%	Equity World Buyback	170
UBS MSCI World Small Cap Socially Responsible UCITS ETF USD dis	0.53%	Equity World Small Cap Climate Change	66
Amundi Core S&P 500 Swap UCITS ETF GBP Hedged Dist	0.02%	Equity United States	1,822
BNP Paribas Easy S&P 500 Scored and Screened UCITS ETF EUR Acc	0.04%	Equity United States Social/Environmental	618
State Street SPDR S&P 500 UCITS ETF USD Unhedged (Acc)	0.02%	Equity United States	17,596
BNP Paribas Easy S&P 500 II UCITS ETF EUR (Acc)	0.02%	Equity United States	559
UBS S&P 500 Climate Transition ESG UCITS ETF hGBP dis	0.01%	Equity United States Social/Environmental Climate Change	1
Xtrackers S&P 500 Equal Weight Scored & Screened UCITS ETF 2C - EUR Hedged	0.51%	Equity United States Equal Weighted	831
iShares S&P 500 3% Capped UCITS ETF USD (Acc)	0.03%	Equity United States	207
Xtrackers S&P 500 Swap UCITS ETF 1D	0.02%	Equity United States	3,919
Xtrackers S&P 500 Equal Weight UCITS ETF 2D	0.29%	Equity United States Equal Weighted	611
Xtrackers S&P 500 Swap II UCITS ETF 1D	0.02%	Equity United States	274
State Street SPDR MSCI All Country World Investable Market UCITS ETF USD Unhedged (Acc)	0.00%	Equity World	8,257
Amundi Global Gender Equality UCITS ETF Acc	1.11%	Equity World Social/Environmental Gender Equality	48
Amundi S&P 500 Swap UCITS ETF USD Dist	0.02%	Equity United States	5
Franklin S&P 500 Screened UCITS ETF Acc	0.03%	Equity United States Social/Environmental Climate Change	4
Vanguard ESG Global All Cap UCITS ETF (USD) Distributing	0.01%	Equity World Social/Environmental	579
CT QR Series US Equity Active UCITS ETF USD Acc	0.13%	Equity United States Fundamental/Quality	82
State Street SPDR S&P 500 UCITS ETF USD Unhedged (Dist)	0.02%	Equity United States	19,450
State Street SPDR S&P 500 UCITS ETF GBP Hedged (Dist)	0.02%	Equity United States	292
iShares S&P 500 3% Capped UCITS ETF EUR Hedged Acc	0.03%	Equity United States	26
iShares S&P 500 Equal Weight UCITS ETF EUR Hedged (Acc)	0.30%	Equity United States Equal Weighted	412
State Street SPDR MSCI All Country World Investable Market UCITS ETF USD Unhedged (Dist)	0.00%	Equity World	239
iShares S&P 500 Equal Weight UCITS ETF GBP Hedged (Acc)	0.30%	Equity United States Equal Weighted	427
Vanguard FTSE Global All-Cap UCITS ETF USD Dist	0.01%	Equity World	87
iShares MSCI USA Small Cap ESG Enhanced CTB UCITS ETF USD (Acc)	0.26%	Equity United States Small Cap	2,472
Amundi Core S&P 500 Swap UCITS ETF EUR Hedged Acc	0.02%	Equity United States	1,770
Xtrackers MSCI World Small Cap UCITS ETF 1C	0.13%	Equity World Small Cap	139
Invesco S&P 500 UCITS ETF GBP Hedged Acc	0.02%	Equity United States	1,880
Vanguard Russell U.S. Mid-Cap UCITS ETF USD Acc	0.10%	Equity United States Mid Cap	4
HSBC MSCI World Small Cap Screened UCITS ETF USD (Acc)	0.27%	Equity World Small Cap	65
BNP Paribas Easy MSCI USA Small Cap Min TE UCITS ETF USD Acc	0.23%	Equity United States Small Cap	41
HSBC S&P 500 UCITS ETF USD	0.02%	Equity United States	9,248
Xtrackers S&P 500 Equal Weight UCITS ETF 3C - CHF Hedged	0.29%	Equity United States Equal Weighted	82
Xtrackers S&P 500 Equal Weight UCITS ETF 2C EUR Hedged	0.29%	Equity United States Equal Weighted	1,317
UBS S&P 500 Scored & Screened UCITS ETF USD acc	0.03%	Equity United States Social/Environmental	2,176
Xtrackers S&P 500 Equal Weight Swap UCITS ETF 1C	0.30%	Equity United States Equal Weighted	9
iShares Healthcare Innovation UCITS ETF	1.42%	Equity World Health Care Social/Environmental Innovation	1,313
iShares S&P 500 Swap UCITS ETF USD (Dist)	0.02%	Equity United States	2,278
Xtrackers S&P 500 Equal Weight Scored & Screened UCITS ETF 1C	0.51%	Equity United States Equal Weighted	1,798
Invesco S&P 500 Equal Weight Swap UCITS ETF Acc	0.30%	Equity United States Equal Weighted	1,020
Xtrackers S&P 500 UCITS ETF 1C - EUR Hedged	0.02%	Equity United States	455
Vanguard FTSE Global Small-Cap UCITS ETF USD Dist	0.13%	Equity World Small Cap	10
State Street World Small Cap Enhanced Active Equity UCITS ETF USD Unhedged (Acc)	0.02%	Equity World Small Cap	173
Invesco S&P 500 Scored & Screened UCITS ETF Acc	0.04%	Equity United States Social/Environmental	3,190
Vanguard S&P 500 UCITS ETF (USD) Accumulating	0.02%	Equity United States	33,371
Xtrackers S&P 500 Equal Weight UCITS ETF 1D - GBP Hedged	0.29%	Equity United States Equal Weighted	245
Xtrackers S&P 500 UCITS ETF 1D - EUR Hedged	0.02%	Equity United States	60
WisdomTree S&P 500	0.02%	Equity United States	194
Invesco S&P 500 Equal Weight UCITS ETF Dist	0.30%	Equity United States Equal Weighted	363
iShares S&P 500 Health Care Sector UCITS ETF (Acc)	0.23%	Equity United States Health Care	2,827
iShares S&P 500 Swap UCITS ETF GBP Hedged (Dist)	0.02%	Equity United States	125
UBS S&P 500 Equal Weight SF UCITS ETF USD dis	0.30%	Equity United States Equal Weighted	0
Xtrackers MSCI World Small Cap ESG UCITS ETF 1C	0.22%	Equity World Small Cap	10
UBS MSCI USA Select Factor Mix UCITS ETF USD acc	0.04%	Equity United States Multi-Factor Strategy	113
Invesco S&P 500 Scored & Screened UCITS ETF EUR Hedged Acc	0.04%	Equity United States Social/Environmental	660
Xtrackers S&P 500 Equal Weight Scored & Screened UCITS ETF 3C - CHF Hedged	0.51%	Equity United States Equal Weighted	87
Amundi Core S&P 500 Swap UCITS ETF CHF Hedged Dist	0.02%	Equity United States	144
AB Global Disruptors Portfolio UCITS ETF USD Acc	0.59%	Equity World Technology Social/Environmental Innovation	5
Xtrackers S&P 500 Equal Weight Scored & Screened UCITS ETF 4C - GBP Hedged	0.51%	Equity United States Equal Weighted	25
Amundi Core S&P 500 UCITS ETF UCITS ETF Acc	0.02%	Equity United States	23
UBS MSCI World Small Cap Socially Responsible UCITS ETF USD acc	0.53%	Equity World Small Cap Climate Change	637
Xtrackers S&P 500 Swap II UCITS ETF 1C	0.02%	Equity United States	5,326
iShares Russell 1000 Value UCITS ETF USD (Acc)	0.04%	Equity United States Value	1,065
Amundi S&P 500 Swap UCITS ETF USD Acc	0.02%	Equity United States	3,453
Xtrackers S&P 500 UCITS ETF 4C	0.02%	Equity United States	2,597
UBS Core S&P 500 UCITS ETF hGBP dis	0.02%	Equity United States	74
Amundi S&P 500 Equal Weight ESG UCITS ETF Acc	0.47%	Equity United States Equal Weighted	2,557
iShares MSCI World Small Cap CTB Enhanced ESG UCITS ETF USD (Acc)	0.16%	Equity World Small Cap	413
Amundi Core S&P 500 Swap UCITS ETF USD Dist	0.02%	Equity United States	4,995
iShares Core S&P 500 UCITS ETF USD (Dist)	0.02%	Equity United States	20,839
Amundi S&P 500 Equal Weight UCITS ETF Acc	0.30%	Equity United States Equal Weighted	108
UBS MSCI World Small Cap UCITS ETF USD acc	0.12%	Equity World Small Cap	41
Invesco S&P 500 Equal Weight UCITS ETF Acc	0.30%	Equity United States Equal Weighted	1,112
JPMorgan BetaBuilders US Small Cap Equity UCITS ETF USD (acc)	0.19%	Equity United States Small Cap	83
Amundi S&P 500 Screened UCITS ETF Acc EUR Hedged	0.04%	Equity United States Social/Environmental	1,377
UBS S&P 500 Scored & Screened UCITS ETF hGBP dis	0.03%	Equity United States Social/Environmental	23
Xtrackers S&P 500 Swap UCITS ETF 7C GBP Hedged	0.02%	Equity United States	2
iShares S&P 500 GBP Hedged UCITS ETF (Acc)	0.02%	Equity United States	1,433
Vanguard Russell 1000 U.S. Value UCITS ETF USD Acc	0.04%	Equity United States Value	149
iShares S&P 500 EUR Hedged UCITS ETF (Acc)	0.02%	Equity United States	9,178
State Street SPDR S&P 500 UCITS ETF EUR Hedged	0.02%	Equity United States	2,773
Vanguard FTSE Global Small-Cap UCITS ETF USD Acc	0.13%	Equity World Small Cap	33
UBS MSCI USA Select Factor Mix UCITS ETF USD dis	0.04%	Equity United States Multi-Factor Strategy	29
Amundi S&P 500 Swap UCITS ETF EUR Hedged Acc	0.02%	Equity United States	903
UBS Core S&P 500 UCITS ETF hEUR acc	0.02%	Equity United States	221
L&G Gerd Kommer Multifactor Equity UCITS ETF USD Distributing	0.01%	Equity World Multi-Factor Strategy	245
UBS MSCI USA Small Cap Selection UCITS ETF USD acc	0.42%	Equity United States Small Cap	227
BNP Paribas Easy S&P 500 II UCITS ETF EUR Hedged (Acc)	0.02%	Equity United States	439
BNP Paribas Easy S&P 500 II UCITS ETF USD (Dist)	0.02%	Equity United States	145
State Street SPDR MSCI World Small Cap UCITS ETF USD Unhedged (Dist)	0.13%	Equity World Small Cap	45
Vanguard FTSE Global All-Cap UCITS ETF USD Acc	0.01%	Equity World	2,585
Invesco S&P 500 UCITS ETF Acc	0.02%	Equity United States	39,515
Xtrackers S&P 500 Scored & Screened UCITS ETF 1C	0.04%	Equity United States Social/Environmental	131
CT QR Series US Equity Active UCITS ETF USD Dist	0.13%	Equity United States Fundamental/Quality	1
Franklin ClearBridge US Smaller Companies UCITS ETF Acc	2.46%	Equity United States Small Cap	5
UBS S&P 500 Scored & Screened UCITS ETF USD dis	0.03%	Equity United States Social/Environmental	448
UBS S&P 500 SF UCITS ETF USD acc	0.02%	Equity United States	204
HSBC S&P 500 UCITS ETF USD (Acc)	0.02%	Equity United States	585
Xtrackers S&P 500 Equal Weight Swap UCITS ETF 1D	0.30%	Equity United States Equal Weighted	24
UBS MSCI USA Select Factor Mix UCITS ETF hCHF acc	0.04%	Equity United States Multi-Factor Strategy	24
Vanguard S&P 500 UCITS ETF (USD) Distributing	0.02%	Equity United States	48,236
iShares S&P 500 Equal Weight UCITS ETF USD (Acc)	0.30%	Equity United States Equal Weighted	4,683
iShares S&P 500 Swap UCITS ETF CHF Hedged (Acc)	0.02%	Equity United States	1
Amundi S&P 500 Equal Weight ESG UCITS ETF EUR Hedged Acc	0.47%	Equity United States Equal Weighted	121
iShares S&P 500 Equal Weight UCITS ETF USD (Dist)	0.30%	Equity United States Equal Weighted	34
Vanguard Russell 1000 U.S. Value UCITS ETF USD Dist	0.04%	Equity United States Value	1
L&G Gerd Kommer Multifactor Equity UCITS ETF USD Accumulating	0.01%	Equity World Multi-Factor Strategy	1,490
State Street SPDR MSCI USA Small Cap Value Weighted UCITS ETF USD	0.20%	Equity United States Small Cap	892
iShares Core S&P 500 UCITS ETF EUR Hedged (Acc)	0.02%	Equity United States	98
Vanguard ESG North America All Cap UCITS ETF (USD) Distributing	0.02%	Equity North America Social/Environmental	31
Invesco Dow Jones Islamic Global Developed Markets UCITS ETF Acc	0.02%	Equity World Islamic Investing	1,061
State Street SPDR S&P U.S. Health Care Select Sector UCITS ETF USD	0.23%	Equity United States Health Care	530
State Street SPDR S&P 500 Leaders UCITS ETF USD Unhedged (Acc)	0.05%	Equity United States Social/Environmental	4,534
WisdomTree S&P 500 EUR Daily Hedged	0.02%	Equity United States	5
Amundi Core S&P 500 Swap UCITS ETF EUR Hedged Dist	0.02%	Equity United States	1,133
Xtrackers S&P 500 Swap UCITS ETF 5C EUR Hedged	0.02%	Equity United States	314
BNP Paribas Easy S&P 500 Scored and Screened UCITS ETF EUR Hedged Acc	0.04%	Equity United States Social/Environmental	63
Xtrackers S&P 500 UCITS ETF 3C CHF hedged	0.02%	Equity United States	68
BNP Paribas Easy S&P 500 Scored and Screened UCITS ETF Acc	0.04%	Equity United States Social/Environmental	226
JPMorgan BetaBuilders US Small Cap Equity UCITS ETF USD (dist)	0.19%	Equity United States Small Cap	230
Invesco S&P 500 EUR Hedged UCITS ETF	0.02%	Equity United States	2,869
iShares Core S&P 500 UCITS ETF GBP Hedged (Dist)	0.02%	Equity United States	1,805
UBS S&P 500 Equal Weight SF UCITS ETF USD acc	0.30%	Equity United States Equal Weighted	13
iShares MSCI World Small Cap UCITS ETF	0.13%	Equity World Small Cap	7,896
iShares Core S&P 500 UCITS ETF USD (Acc)	0.02%	Equity United States	141,385
iShares S&P 500 Scored and Screened UCITS ETF USD (Acc)	0.04%	Equity United States Social/Environmental	468
iShares S&P 500 Health Care Sector UCITS ETF EUR Hedged (Dist)	0.23%	Equity United States Health Care	122
iShares S&P 500 3% Capped UCITS ETF USD (Dist)	0.03%	Equity United States	1
Vanguard ESG North America All Cap UCITS ETF (USD) Accumulating	0.02%	Equity North America Social/Environmental	273
BNP Paribas Easy S&P 500 II UCITS ETF USD (Acc)	0.02%	Equity United States	2,671
Amundi Core S&P 500 Swap UCITS ETF Acc	0.02%	Equity United States	17,381
L&G Healthcare Technology & Innovation UCITS ETF USD Acc	1.93%	Equity World Health Care Innovation	306
iShares S&P 500 Scored and Screened UCITS ETF EUR Hedged (Acc)	0.04%	Equity United States Social/Environmental	417
UBS Core S&P 500 UCITS ETF USD acc	0.02%	Equity United States	2,192
Invesco S&P 500 UCITS ETF Dist	0.02%	Equity United States	9,389
Xtrackers US Equity Enhanced Active UCITS ETF 1C	0.07%	Equity United States Social/Environmental	644
UBS S&P 500 Scored & Screened UCITS ETF hEUR acc	0.03%	Equity United States Social/Environmental	872
BNP Paribas Easy MSCI USA Small Cap Min TE UCITS ETF EUR Acc	0.23%	Equity United States Small Cap	30
State Street SPDR MSCI World Small Cap UCITS ETF USD Unhedged (Acc)	0.13%	Equity World Small Cap	1,733
Amundi S&P 500 Swap UCITS ETF EUR Acc	0.02%	Equity United States	3,023
Amundi Core S&P 500 Swap UCITS ETF EUR Dist	0.02%	Equity United States	3,419
UBS S&P 500 Climate Transition ESG UCITS ETF USD acc	0.01%	Equity United States Social/Environmental Climate Change	5
UBS S&P 500 Climate Transition ESG UCITS ETF hEUR acc	0.01%	Equity United States Social/Environmental Climate Change	1
Xtrackers MSCI World IMI UCITS ETF 1C Capitalisation	0.01%	Equity World	24
Xtrackers S&P 500 UCITS ETF 4D	0.02%	Equity United States	1
Vanguard ESG Global All Cap UCITS ETF (USD) Accumulating	0.01%	Equity World Social/Environmental	1,139
Vanguard Russell U.S. Mid-Cap UCITS ETF USD Dist	0.10%	Equity United States Mid Cap	3
Amundi S&P 500 Screened UCITS ETF Acc	0.04%	Equity United States Social/Environmental	4,127
UBS Core S&P 500 UCITS ETF USD dis	0.02%	Equity United States	1,314
Xtrackers S&P 500 UCITS ETF 2C - GBP Hedged	0.02%	Equity United States	737
UBS Core S&P 500 UCITS ETF hCHF acc	0.02%	Equity United States	766
HSBC S&P 500 UCITS ETF CHF Hedged (Acc)	0.02%	Equity United States	12

Performance

Returns overview

YTD	+51.61%
1 month	+11.15%
3 months	+31.10%
6 months	+74.67%
1 year	+76.31%
3 years	+44.77%
5 years	-24.06%
Since inception (MAX)	+408.26%
2025	+2.72%
2024	-20.81%
2023	+1.04%
2022	-33.87%

Monthly returns in a heat map

Risk

Risk metrics in this section:

Volatility, annualised, measured for 1, 3 and 5 year periods. The annualised volatility reflects the degree of price fluctuations during a one year period. The higher the volatility, the more significantly the price of the asset (stock, ETF, etc.) has changed in the past. Assets with higher volatility are generally considered more risky. We calculate the volatility based on the data for the past 1, 3 and 5 years so that you can see if price fluctuations for the ETF became stronger or weaker over time.
Return per risk for 1, 3 and 5 year periods. This is the annualised (i.e. converted to a one year period) past return divided by the past annualised volatility. The metric puts the historical return of an asset in relation to its historical risk and gives you a retrospective indication of the degree of price fluctuation you had to bear with in order to obtain the return. We calculate this parameter for 1, 3 and 5 year periods to display its evolution over time.
Maximum drawdown for a period. This shows the worst possible loss an investor could have suffered during the respective period, by first buying and subsequently selling the asset at the least favourable prices. For example, if there was the following sequence of daily ETF prices: 10€, 5€, 12€, 20€, an investor would have suffered the worst loss by buying for 10€ and subsequently selling for 5€. Therefore in this case the maximum drawdown would be (5€ - 10€)/10€ = -50%.

ETF returns include dividend payments (if applicable).