Ionis Pharmaceuticals, Inc.

ISIN US4622221004

 | 

WKN A2ACMZ

Market cap (in EUR)
11,380 m
Country
United States
Sector
Healthcare
Dividend yield
0.00%
 

Overview

Quote

Description

Ionis Pharmaceuticals, Inc. engages in the development and commercialization of human therapeutic drugs using antisense technology. The company was founded by Stanley T. Crooke, David J. Ecker, Christopher K. Mirabelli, and Brett P. Monia on January 10, 1989 and is headquartered in Carlsbad, CA.
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Healthcare Biopharmaceuticals Other Biopharmaceuticals United States

Chart

Financials

Key metrics

Market capitalisation, EUR 11,380 m
EPS, EUR -1.81
P/B ratio 26.4
P/E ratio -
Dividend yield 0.00%

Income statement (2025)

Revenue, EUR 837 m
Net income, EUR -338 m
Profit margin -40.41%
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Capital at risk

What ETF is Ionis Pharmaceuticals, Inc. in?

There are 54 ETFs which contain Ionis Pharmaceuticals, Inc.. All of these ETFs are listed in the table below. The ETF with the largest weighting of Ionis Pharmaceuticals, Inc. is the VanEck Genomics and Healthcare Innovators UCITS ETF A.
ETF Weight Investment focus Fund size (in m EUR)
Amundi MSCI World Small Cap ESG Broad Transition UCITS ETF Acc 0.16%
Equity
World
Small Cap
Climate Change
476
JPMorgan BetaBuilders US Small Cap Equity UCITS ETF USD (acc) 0.16%
Equity
United States
Small Cap
72
UBS MSCI USA Select Factor Mix UCITS ETF hEUR acc 0.03%
Equity
United States
Multi-Factor Strategy
8
JPMorgan US Value Equity Active UCITS ETF USD (acc) 0.13%
Equity
United States
Value
70
JPMorgan US Value Equity Active UCITS ETF EUR Hedged (acc) 0.13%
Equity
United States
Value
4
VanEck Morningstar US SMID Moat UCITS ETF A 0.62%
Equity
United States
Small Cap
Moat
11
Xtrackers MSCI World Small Cap UCITS ETF 1D 0.11%
Equity
World
Small Cap
11
WisdomTree BioRevolution UCITS ETF USD Acc 2.03%
Equity
World
Health Care
Social/Environmental
Biotech
15
UBS MSCI USA Select Factor Mix UCITS ETF USD dis 0.03%
Equity
United States
Multi-Factor Strategy
28
L&G Gerd Kommer Multifactor Equity UCITS ETF USD Distributing 0.00%
Equity
World
Multi-Factor Strategy
214
iShares US Equity Enhanced Active UCITS ETF EUR Hedged (Acc) 0.03%
Equity
United States
Social/Environmental
Multi-Asset Strategy
8
UBS MSCI USA Small Cap Selection UCITS ETF USD acc 0.38%
Equity
United States
Small Cap
291
Amundi Russell 1000 Growth UCITS ETF Acc 0.04%
Equity
United States
Growth
540
State Street SPDR MSCI World Small Cap UCITS ETF USD Unhedged (Dist) 0.11%
Equity
World
Small Cap
38
iShares Russell 1000 Growth UCITS ETF USD (Acc) 0.03%
Equity
United States
Growth
983
CT QR Series US Equity Active UCITS ETF USD Dist 0.02%
Equity
United States
Fundamental/Quality
-
State Street SPDR MSCI All Country World Investable Market UCITS ETF USD Unhedged (Acc) 0.04%
Equity
World
6,043
ARK Genomic Revolution UCITS ETF USD Accumulating 1.98%
Equity
World
Health Care
Innovation
63
Vanguard ESG Global All Cap UCITS ETF (USD) Distributing 0.02%
Equity
World
Social/Environmental
584
CT QR Series US Equity Active UCITS ETF USD Acc 0.02%
Equity
United States
Fundamental/Quality
-
Invesco Nasdaq Next Generation 100 UCITS ETF Acc 0.60%
Equity
United States
44
First Trust US IPO Index UCITS ETF Acc 0.16%
Equity
United States
IPO
16
State Street SPDR MSCI All Country World Investable Market UCITS ETF USD Unhedged (Dist) 0.04%
Equity
World
146
UBS MSCI USA Select Factor Mix UCITS ETF hCHF acc 0.03%
Equity
United States
Multi-Factor Strategy
25
iShares MSCI USA Small Cap ESG Enhanced CTB UCITS ETF USD (Acc) 0.24%
Equity
United States
Small Cap
2,748
Xtrackers MSCI World Small Cap UCITS ETF 1C 0.11%
Equity
World
Small Cap
131
iShares World Equity Factor Rotation Active UCITS ETF USD (Acc) 0.02%
Equity
World
Multi-Factor Strategy
216
iShares Nasdaq US Biotechnology UCITS ETF USD (Dist) 1.00%
Equity
United States
Health Care
Biotech
53
L&G Gerd Kommer Multifactor Equity UCITS ETF USD Accumulating 0.00%
Equity
World
Multi-Factor Strategy
1,296
State Street SPDR MSCI USA Small Cap Value Weighted UCITS ETF USD 0.01%
Equity
United States
Small Cap
904
Vanguard ESG North America All Cap UCITS ETF (USD) Distributing 0.02%
Equity
North America
Social/Environmental
26
Invesco Dow Jones Islamic Global Developed Markets UCITS ETF Acc 0.02%
Equity
World
Islamic Investing
937
HSBC MSCI World Small Cap Screened UCITS ETF USD (Acc) 0.25%
Equity
World
Small Cap
135
BNP Paribas Easy MSCI USA Small Cap Min TE UCITS ETF USD Acc 0.19%
Equity
United States
Small Cap
37
JPMorgan US Value Equity Active UCITS ETF USD (dist) 0.13%
Equity
United States
Value
6
Harbor Health Care UCITS ETF Accumulating 0.69%
Equity
World
Health Care
Innovation
13
JPMorgan BetaBuilders US Small Cap Equity UCITS ETF USD (dist) 0.16%
Equity
United States
Small Cap
230
iShares US Equity Enhanced Active UCITS ETF GBP Hedged (Acc) 0.03%
Equity
United States
Social/Environmental
Multi-Asset Strategy
0
iShares MSCI World Small Cap UCITS ETF 0.11%
Equity
World
Small Cap
7,485
Vanguard ESG North America All Cap UCITS ETF (USD) Accumulating 0.02%
Equity
North America
Social/Environmental
242
Xtrackers World Small Cap Green Tech Innovators UCITS ETF 1C 0.67%
Equity
World
Small Cap
Innovation
72
WisdomTree Megatrends UCITS ETF USD 0.14%
Equity
World
Social/Environmental
Innovation
61
VanEck Genomics and Healthcare Innovators UCITS ETF A 2.80%
Equity
World
Health Care
Social/Environmental
Innovation
10
Xtrackers MSCI World Small Cap ESG UCITS ETF 1C 0.17%
Equity
World
Small Cap
10
BNP Paribas Easy MSCI USA Small Cap Min TE UCITS ETF EUR Acc 0.19%
Equity
United States
Small Cap
62
UBS MSCI USA Select Factor Mix UCITS ETF USD acc 0.03%
Equity
United States
Multi-Factor Strategy
114
State Street SPDR MSCI World Small Cap UCITS ETF USD Unhedged (Acc) 0.11%
Equity
World
Small Cap
1,689
iShares Nasdaq US Biotechnology UCITS ETF 1.00%
Equity
United States
Health Care
Biotech
862
iShares MSCI World Small Cap CTB Enhanced ESG UCITS ETF USD (Acc) 0.13%
Equity
World
Small Cap
383
Xtrackers MSCI World IMI UCITS ETF 1C Capitalisation 0.02%
Equity
World
12
Vanguard ESG Global All Cap UCITS ETF (USD) Accumulating 0.02%
Equity
World
Social/Environmental
940
WisdomTree Tech Megatrends UCITS ETF USD Acc 0.37%
Equity
World
Technology
Social/Environmental
Innovation
8
L&G Pharma Breakthrough UCITS ETF 2.70%
Equity
World
Health Care
Innovation
18
iShares US Equity Enhanced Active UCITS ETF USD (Acc) 0.03%
Equity
United States
Social/Environmental
Multi-Asset Strategy
1,366

Performance

Returns overview

YTD -7.02%
1 month -0.52%
3 months -1.31%
6 months -6.95%
1 year +105.88%
3 years +69.20%
5 years +105.57%
Since inception (MAX) +17.05%
2025 +109.42%
2024 -28.88%
2023 +28.14%
2022 +36.82%

Monthly returns in a heat map

Risk

Risk metrics in this section:
 
  • Volatility, annualised, measured for 1, 3 and 5 year periods. The annualised volatility reflects the degree of price fluctuations during a one year period. The higher the volatility, the more significantly the price of the asset (stock, ETF, etc.) has changed in the past. Assets with higher volatility are generally considered more risky. We calculate the volatility based on the data for the past 1, 3 and 5 years so that you can see if price fluctuations for the ETF became stronger or weaker over time.
  • Return per risk for 1, 3 and 5 year periods. This is the annualised (i.e. converted to a one year period) past return divided by the past annualised volatility. The metric puts the historical return of an asset in relation to its historical risk and gives you a retrospective indication of the degree of price fluctuation you had to bear with in order to obtain the return. We calculate this parameter for 1, 3 and 5 year periods to display its evolution over time.
  • Maximum drawdown for a period. This shows the worst possible loss an investor could have suffered during the respective period, by first buying and subsequently selling the asset at the least favourable prices. For example, if there was the following sequence of daily ETF prices: 10€, 5€, 12€, 20€, an investor would have suffered the worst loss by buying for 10€ and subsequently selling for 5€. Therefore in this case the maximum drawdown would be (5€ - 10€)/10€ = -50%.
ETF returns include dividend payments (if applicable).
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Risk overview

Volatility 1 year 48.25%
Volatility 3 years 41.59%
Volatility 5 years 41.19%
Return per risk 1 year 2.33
Return per risk 3 years 0.62
Return per risk 5 years 0.42
Maximum drawdown 1 year -17.98%
Maximum drawdown 3 years -52.53%
Maximum drawdown 5 years -52.53%
Maximum drawdown since inception -72.16%

Rolling 1 year volatility

— Data provided by Trackinsight, etfinfo, Xignite Inc., gettex, FactSet and justETF GmbH.

Quotes are either real-time (gettex) or 15 minutes delayed stock exchange quotes or NAVs (daily published by the fund provider). By default, ETF returns include dividend payments (if applicable). There is no warranty for completeness, accuracy and correctness for the displayed information.