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How to invest in USA using ETFs
How do I invest in American stocks?
The easiest way to invest in the whole American stock market is to invest in a broad market index. This can be done at low cost by using ETFs.
On the American stock market you'll find 2 indices which are tracked by ETFs. Besides these indices 9 alternative indices on small and mid caps as well as equity strategies can be considered. Among these strategies you find dividend focused, growth and value approaches.
Alternatively, you may consider indices on North America or the World.
Performance of American stocks (S&P 500®)
1 month: -0,20%
1 year: 2,33%
3 years: 57,45%
5 years: 105,03%
Indices in comparison
The best indices for ETFs on USA
For an investment in the American stock market, there are 2 indices available which are tracked by 7 ETFs. On the MSCI USA index there are 2 ETFs. On the S&P 500® index there are 5 ETFs. The total expense ratio (TER) of ETFs on these indices is between 0,03% p.a. and 0,13% p.a..
| Index | Investment focus | Number of ETFs | Number of constituents | Short description |
|---|---|---|---|---|
MSCI USA | Verenigde Staten | 2 ETFs | 544 (28/11/2025) | The MSCI USA index tracks the leading stocks on the US market. Index factsheet |
S&P 500® | Verenigde Staten | 5 ETFs | 500 | The S&P 500® index tracks the 500 largest US stocks. Index factsheet |
| ETF ISIN | Fund size in m EUR | TER in % | Use of profits | Fund domicile | Replication method | |
|---|---|---|---|---|---|---|
| Vanguard S&P 500 UCITS ETF (USD) DistributingIE00B3XXRP09 | 42.952 | 0,07% p.a. | Distribueren | Ierland | Volledige replicatie | |
| Vanguard S&P 500 UCITS ETF (USD) AccumulatingIE00BFMXXD54 | 25.263 | 0,07% p.a. | Accumulerend | Ierland | Volledige replicatie | |
| iShares Core S&P 500 UCITS ETF USD (Dist)IE0031442068 | 17.422 | 0,07% p.a. | Distribueren | Ierland | Volledige replicatie | |
| Amundi Core S&P 500 Swap UCITS ETF EUR DistLU0496786574 | 2.859 | 0,05% p.a. | Distribueren | Luxemburg | Niet-gefinancierde swap | |
| UBS Core MSCI USA UCITS ETF USD disIE00B77D4428 | 1.192 | 0,06% p.a. | Distribueren | Ierland | Volledige replicatie | |
| BNP Paribas Easy S&P 500 UCITS ETFFR0011550680 | 239 | 0,13% p.a. | Distribueren | Frankrijk | Niet-gefinancierde swap | |
| Amundi Core MSCI USA UCITS ETF DistIE000IEGVMH6 | - | 0,03% p.a. | Distribueren | Ierland | Volledige replicatie |
Source: justETF.com; As of 30/11/2025; Calculations in EUR based on the largest ETF of the respective index.
The best USA ETFs
by 1 year return
| 1 | Amundi Core S&P 500 Swap UCITS ETF EUR Dist | 5,23% |
| 2 | Amundi Core MSCI USA UCITS ETF Dist | 5,18% |
| 3 | iShares Core S&P 500 UCITS ETF USD (Dist) | 4,76% |
The cheapest USA ETFs
by total expense ratio (TER)
| 1 | Amundi Core MSCI USA UCITS ETF Dist | 0,03% p.a. |
| 2 | Amundi Core S&P 500 Swap UCITS ETF EUR Dist | 0,05% p.a. |
| 3 | UBS Core MSCI USA UCITS ETF USD dis | 0,06% p.a. |
Alternative investment opportunities
USA indices on small and mid caps or equity strategies
Alternatively, you may consider indices on small and mid caps or equity strategies. Below, we selected 9 alternative USA indices, which are tracked by 9 ETFs as an example. The total expense ratio (TER) of ETFs on alternative USA indices is between 0,07% p.a. and 0,35% p.a..
| Index | Investment focus | Number of ETFs | Number of constituents | Short description |
|---|---|---|---|---|
| Foxberry Sustainability Consensus US | Verenigde Staten Sociaal/Milieu | 1 ETF | 431 (28/06/2024) | The Foxberry Sustainability Consensus US index tracks stocks from the US. Securities are selected according to sustainability criteria and EU directives on climate protection. Index factsheet |
| MSCI USA Enhanced Value | Verenigde Staten Waarde | 1 ETF | 150 (28/06/2024) | The MSCI USA Enhanced Value index tracks the US value stocks. These are U.S. equities which are determined as value stocks using eight historical and forward-looking fundamental data points. Index factsheet |
| MSCI USA High Dividend Yield Advanced Select | Verenigde Staten Dividend | 1 ETF | 93 (28/06/2024) | The MSCI USA High Dividend Yield Advanced Select index tracks high dividend paying US stocks. The stocks included are filtered according to ESG criteria (environmental, social and corporate governance). The parent index is the MSCI USA index. Index factsheet |
| MSCI USA Momentum | Verenigde Staten Momentum | 1 ETF | 125 (28/06/2024) | The MSCI USA Momentum index tracks stocks with a high price momentum from the United States. The index consists of titles that have experienced price increases over the past 6 and past 12 months with the assumption that increases will continue in the future. Index factsheet |
| MSCI USA SRI Select Reduced Fossil Fuels | Verenigde Staten Sociaal/Milieu | 1 ETF | 176 (28/06/2024) | The MSCI USA SRI Select Reduced Fossil Fuels index tracks US stocks considering only companies with very high Environmental, Social and Governance (ESG) ratings relative to their sector peers, to ensure the inclusion of the best of class companies from an ESG perspective and avoiding companies incompatible with values screen or having exposure to fossil fuels through extraction and production activities, power generation activities or reserves ownership. The weight of each company is capped to 5%. Index factsheet |
| MSCI USA Screened | Verenigde Staten Sociaal/Milieu | 1 ETF | 541 (28/06/2024) | The MSCI USA Screened index tracks US companies. The index excludes companies that are involved in businesses related to thermal coal, controversial weapons, tobacco and other controversial industries. Index factsheet |
| S&P 500 Minimum Volatility | Verenigde Staten Lage volatiliteit/Risico-gewogen | 1 ETF | 79 (28/06/2024) | The S&P 500 Minimum Volatility index tracks an optimized portfolio that includes a selection of stocks where volatility is among the lowest in the S&P 500. The S&P 500 index tracks large cap US stocks. Index factsheet |
| S&P 500® Equal Weight | Verenigde Staten Equal Weighted | 1 ETF | 500 | The S&P 500® Equal Weight (EWI) index tracks large cap US stocks equally weighted with a fixed weight of 0.20%. Index factsheet |
| S&P SmallCap 600 | Verenigde Staten Small Cap | 1 ETF | 600 | The S&P SmallCap 600 index tracks 600 small cap US stocks. Index factsheet |
| ETF ISIN | Fund size in m EUR | TER in % | Use of profits | Fund domicile | Replication method | |
|---|---|---|---|---|---|---|
| iShares S&P SmallCap 600 UCITS ETFIE00B2QWCY14 | 1.745 | 0,30% p.a. | Distribueren | Ierland | Geoptimaliseerde sampling | |
| iShares MSCI USA Screened UCITS ETF USD (Dist)IE00BFNM3H51 | 1.336 | 0,07% p.a. | Distribueren | Ierland | Volledige replicatie | |
| Invesco S&P 500 Equal Weight Swap UCITS ETF AccIE0000TZZ2B2 | 622 | 0,20% p.a. | Accumulerend | Ierland | Niet-gefinancierde swap | |
| iShares MSCI USA Quality Dividend Advanced UCITS ETF USD (Dist)IE00BKM4H312 | 555 | 0,35% p.a. | Distribueren | Ierland | Volledige replicatie | |
| iShares MSCI USA SRI UCITS ETF USD (Dist)IE00BZ173T46 | 334 | 0,20% p.a. | Distribueren | Ierland | Volledige replicatie | |
| L&G US ESG Exclusions Paris Aligned UCITS ETF USD AccumulatingIE00BKLWY790 | 166 | 0,12% p.a. | Accumulerend | Ierland | Volledige replicatie | |
| iShares Edge MSCI USA Value Factor UCITS ETF USD (Dist)IE00BFF5RX68 | 107 | 0,20% p.a. | Distribueren | Ierland | Volledige replicatie | |
| iShares Edge S&P 500 Minimum Volatility UCITS ETF USD (Dist)IE00BD93YH54 | 98 | 0,20% p.a. | Distribueren | Ierland | Geoptimaliseerde sampling | |
| iShares Edge MSCI USA Momentum Factor UCITS ETF USD (Dist)IE00BFF5RZ82 | 12 | 0,20% p.a. | Distribueren | Ierland | Volledige replicatie |
| Index | 1 month in % | 3 months in % | 6 months in % | 1 year in % | 3 years in % | |
|---|---|---|---|---|---|---|
| S&P SmallCap 600 | 2,58% | 3,45% | 12,99% | -11,23% | 10,19% | |
| MSCI USA SRI Select Reduced Fossil Fuels | -1,26% | 3,25% | 5,95% | -4,85% | 29,33% | |
| S&P 500 Minimum Volatility | 1,47% | 4,09% | 4,61% | -3,06% | 24,65% | |
| MSCI USA High Dividend Yield Advanced Select | 0,54% | 5,69% | 11,40% | -0,50% | 29,12% | |
| MSCI USA Momentum | -1,23% | 4,78% | 5,89% | 3,74% | 45,89% | |
| MSCI USA Screened | 0,18% | 7,47% | 14,91% | 5,36% | 62,52% | |
| Foxberry Sustainability Consensus US | -0,05% | 7,88% | 15,65% | 6,59% | 63,37% | |
| MSCI USA Enhanced Value | 3,10% | 13,13% | 23,54% | 8,87% | 31,02% | |
| S&P 500® Equal Weight | 2,04% | 2,73% | 7,13% | - | - |
| Index | 2025 in % | 2024 in % | 2023 in % | 2022 in % | 2021 in % | |
|---|---|---|---|---|---|---|
| S&P SmallCap 600 | -4,61% | 14,93% | 11,40% | -11,57% | 36,77% | |
| MSCI USA SRI Select Reduced Fossil Fuels | -1,79% | 20,77% | 19,58% | -13,67% | 41,27% | |
| S&P 500 Minimum Volatility | -0,89% | 25,96% | 5,93% | -5,46% | 34,02% | |
| MSCI USA High Dividend Yield Advanced Select | 3,68% | 22,57% | 9,96% | -0,65% | 31,03% | |
| MSCI USA Momentum | 4,18% | 40,28% | 5,06% | -12,61% | 21,99% | |
| MSCI USA Screened | 5,76% | 34,21% | 25,24% | -16,00% | 37,90% | |
| Foxberry Sustainability Consensus US | 5,96% | 33,87% | 25,52% | -18,15% | 37,09% | |
| MSCI USA Enhanced Value | 14,70% | 13,59% | 9,57% | -9,20% | 39,34% | |
| S&P 500® Equal Weight | - | - | - | - | - |
Source: justETF.com; As of 30/11/2025; Calculations in EUR based on the largest ETF of the respective index.
North America indices with a large share of USA
Besides USA ETFs you may invest in ETFs on the North American stock market. In total, you can invest in 2 North America indices, which are tracked by 3 ETFs. The total expense ratio (TER) of ETFs on North America is between 0,08% p.a. and 0,40% p.a..
| Index | Investment focus | Number of ETFs | Number of constituents | Short description |
|---|---|---|---|---|
| FTSE North America | Noord-Amerika USA: 95.69% (30/11/2022) | 2 ETFs | 627 (28/06/2024) | The FTSE North America index tracks stocks from the USA and Canada. Index factsheet |
| MSCI North America | Noord-Amerika USA: 95.21% (30/11/2022) | 1 ETF | 627 (28/11/2025) | The MSCI North America index tracks stocks from developed North American countries (Canada and United States). Index factsheet |
| ETF ISIN | Fund size in m EUR | TER in % | Use of profits | Fund domicile | Replication method | |
|---|---|---|---|---|---|---|
| Vanguard FTSE North America UCITS ETF (USD) DistributingIE00BKX55R35 | 2.430 | 0,08% p.a. | Distribueren | Ierland | Volledige replicatie | |
| Vanguard FTSE North America UCITS ETF (USD) AccumulatingIE00BK5BQW10 | 2.015 | 0,08% p.a. | Accumulerend | Ierland | Volledige replicatie | |
| iShares MSCI North America UCITS ETFIE00B14X4M10 | 1.105 | 0,40% p.a. | Distribueren | Ierland | Volledige replicatie |
| Index | 1 month in % | 3 months in % | 6 months in % | 1 year in % | 3 years in % | |
|---|---|---|---|---|---|---|
| MSCI North America | 0,37% | 6,96% | 13,90% | 4,56% | 54,74% | |
| FTSE North America | 0,40% | 7,03% | 13,99% | 5,06% | 56,58% |
| Index | 2025 in % | 2024 in % | 2023 in % | 2022 in % | 2021 in % | |
|---|---|---|---|---|---|---|
| MSCI North America | 5,61% | 31,68% | 21,38% | -14,59% | 36,78% | |
| FTSE North America | 6,06% | 32,17% | 21,81% | -14,27% | 37,15% |
Source: justETF.com; As of 30/11/2025; Calculations in EUR based on the largest ETF of the respective index.
Global indices with a large share of USA
As further alternative you may invest in global stock markets. In total, you can invest in 3 global indices, which are tracked by 9 ETFs. The total expense ratio (TER) of ETFs on global indices is between 0,06% p.a. and 0,50% p.a..
| Index | Investment focus | Number of ETFs | Number of constituents | Short description |
|---|---|---|---|---|
| FTSE Developed | Wereld USA: 66.94% (30/11/2022) | 2 ETFs | 1.976 (31/03/2025) | The FTSE Developed index tracks the largest stocks in developed markets across the world. Index factsheet |
| MSCI All Country World (ACWI) | Wereld USA: 61.65% (30/11/2022) | 1 ETF | 2.517 (28/11/2025) | The MSCI All Country World Index (ACWI) tracks large- and mid-cap stocks from 23 developed and 24 emerging markets worldwide. Index factsheet |
| MSCI World | Wereld USA: 69.17% (30/11/2022) | 6 ETFs | 1.321 (28/11/2025) | The MSCI World index tracks stocks from 23 developed countries worldwide. Index factsheet |
| ETF ISIN | Fund size in m EUR | TER in % | Use of profits | Fund domicile | Replication method | |
|---|---|---|---|---|---|---|
| iShares MSCI ACWI UCITS ETF USD (Acc)IE00B6R52259 | 20.831 | 0,20% p.a. | Accumulerend | Ierland | Geoptimaliseerde sampling | |
| iShares MSCI World UCITS ETF (Dist)IE00B0M62Q58 | 7.468 | 0,50% p.a. | Distribueren | Ierland | Geoptimaliseerde sampling | |
| Amundi MSCI World Swap II UCITS ETF DistFR0010315770 | 7.399 | 0,30% p.a. | Distribueren | Frankrijk | Niet-gefinancierde swap | |
| UBS Core MSCI World UCITS ETF USD accIE00BD4TXV59 | 4.695 | 0,06% p.a. | Accumulerend | Ierland | Volledige replicatie | |
| Vanguard FTSE Developed World UCITS ETF AccIE00BK5BQV03 | 4.695 | 0,12% p.a. | Accumulerend | Ierland | Geoptimaliseerde sampling | |
| Xtrackers MSCI World UCITS ETF 1DIE00BK1PV551 | 4.440 | 0,12% p.a. | Distribueren | Ierland | Geoptimaliseerde sampling | |
| Vanguard FTSE Developed World UCITS ETF DistributingIE00BKX55T58 | 3.506 | 0,12% p.a. | Distribueren | Ierland | Geoptimaliseerde sampling | |
| UBS Core MSCI World UCITS ETF USD disIE00B7KQ7B66 | 1.204 | 0,06% p.a. | Distribueren | Ierland | Volledige replicatie | |
| Amundi Core MSCI World UCITS ETF USD DistIE000CNSFAR2 | 820 | 0,12% p.a. | Distribueren | Ierland | Volledige replicatie |
| Index | 1 month in % | 3 months in % | 6 months in % | 1 year in % | 3 years in % | |
|---|---|---|---|---|---|---|
| MSCI World | 0,32% | 6,33% | 12,02% | 6,54% | 50,53% | |
| FTSE Developed | 0,31% | 6,67% | 12,59% | 7,76% | 52,17% | |
| MSCI All Country World (ACWI) | -0,02% | 6,74% | 12,71% | 7,97% | 49,88% |
| Index | 2025 in % | 2024 in % | 2023 in % | 2022 in % | 2021 in % | |
|---|---|---|---|---|---|---|
| MSCI World | 7,72% | 25,92% | 19,24% | -13,24% | 31,63% | |
| MSCI All Country World (ACWI) | 8,79% | 24,82% | 18,11% | -13,12% | 28,60% | |
| FTSE Developed | 8,83% | 25,35% | 19,54% | -12,98% | 31,08% |
Source: justETF.com; As of 30/11/2025; Calculations in EUR based on the largest ETF of the respective index.