The best Innovation ETFs

How to invest in innovative technologies using ETFs

0.15% p.a. - 0.70% p.a.
annual total expense ratio (TER) of innovation ETFs
on innovative technologies, which are tracked by ETFs
on innovative technologies
The best indices for innovation ETFs

How do I invest in innovative technologies?

Gaining new insights through research and using these insights to develop and implement new technologies is part of the business model of many companies.

Many of these efforts, with particular economic impact and dissemination, are expected to be in the health sector. The same applies to digital technologies, whose effects will probably not result in evolution but in a complete transformation of value chains and sales processes. Index providers evaluate companies according to their ambitions for innovation and construct specific indices based on this information.

In this investment guide, you will find all ETFs that allow you to invest in innovative technologies. Currently, there are 9 ETFs available.

iSTOXX® FactSet Breakthrough Healthcare performance

1 month: 5.27%
1 year: 41.03%
3 years: 54.28%

Innovation ETFs in comparison

The most important factors at a glance

When choosing an innovation ETF one should consider several other factors in addition to the methodology of the underlying index and performance of an ETF. For better comparison, you will find a list of all innovation ETFs with details on size, cost, age, income, domicile and replication method ranked by fund size.

Compare all innovation ETFs in detail
Compare all innovation ETFs in a chart

  Fund size
in m GBP
in %
Use of profits Fund domicile Replication method
iShares Healthcare Innovation UCITS ETFIE00BYZK4776 1,645 0.40% p.a. Accumulating Ireland Optimized sampling
Lyxor MSCI Disruptive Technology ESG Filtered (DR) UCITS ETF - AccLU2023678282 243 0.15% p.a. Accumulating Luxembourg Full replication
L&G Healthcare Breakthrough UCITS ETF USD AccIE00BK5BC677 155 0.49% p.a. Accumulating Ireland Full replication
HANetf HAN-GINS Tech Megatrend Equal Weight UCITS ETFIE00BDDRF700 90 0.59% p.a. Accumulating Ireland Sampling
L&G Pharma Breakthrough UCITS ETFIE00BF0H7608 22 0.49% p.a. Accumulating Ireland Full replication
HANetf HAN-GINS Indxx Healthcare Megatrend Equal Weight UCITS ETFIE00BJQTJ848 14 0.59% p.a. Accumulating Ireland Full replication
Global X Telemedicine & Digital Health UCITS ETF Acc USDIE00BLR6QB00 8 0.68% p.a. Accumulating Ireland Full replication
First Trust Indxx NextG UCITS ETF AccIE00BWTNM743 3 0.70% p.a. Accumulating Ireland Full replication
Global X Telemedicine & Digital Health UCITS ETF Dist GBPIE00BLR6QC17 1 0.68% p.a. Distributing Ireland Full replication

Source:; As of 19/04/2021


Return comparison of all innovation ETFs

The table shows the returns of all innovation ETFs in comparison. All return figures are including dividends as of month end. Besides the return the reference date on which you conduct the comparison is important. In order to find the best ETFs, you can also perform a chart comparison.

Source:; As of 31/03/2021; Calculations in GBP including dividends