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The best Innovation ETFs
How to invest in innovative technologies using ETFs
0.30% p.a. - 0.89% p.a.
annual total expense ratio (TER) of innovation ETFs
on innovative technologies, which are tracked by ETFs
on innovative technologies
How do I invest in innovative technologies?
Gaining new insights through research and using these insights to develop and implement new technologies is part of the business model of many companies.Many of these efforts, with particular economic impact and dissemination, are expected to be in the health sector. The same applies to digital technologies, whose effects will probably not result in evolution but in a complete transformation of value chains and sales processes. Index providers evaluate companies according to their ambitions for innovation and construct specific indices based on this information.
In this investment guide, you will find all ETFs that allow you to invest in innovative technologies. Currently, there are 24 ETFs available.
iSTOXX® FactSet Breakthrough Healthcare performance
1 month: 3.99%
1 year: 9.89%
3 years: 9.18%
5 years: -5.70%
Innovation ETFs in comparison
The most important factors at a glance
When choosing an innovation ETF one should consider several other factors in addition to the methodology of the underlying index and performance of an ETF. For better comparison, you will find a list of all innovation ETFs with details on size, cost, age, income, domicile and replication method ranked by fund size.
Compare all innovation ETFs in detail
Compare all innovation ETFs in a chart
| Provider ISIN | Fund size in m GBP | TER in % | Use of profits | Fund domicile | Replication method | |
|---|---|---|---|---|---|---|
| iShares Healthcare Innovation UCITS ETFIE00BYZK4776 | 804 | 0.40% p.a. | Accumulating | Ireland | Optimized sampling | |
| UBS Solactive China Technology UCITS ETF USD accLU2265794276 | 480 | 0.47% p.a. | Accumulating | Luxembourg | Full replication | |
| ARK Innovation UCITS ETF USD AccumulatingIE000GA3D489 | 267 | 0.75% p.a. | Accumulating | Ireland | Full replication | |
| Amundi MSCI Disruptive Technology UCITS ETF AccLU2023678282 | 134 | 0.45% p.a. | Accumulating | Luxembourg | Full replication | |
| L&G Healthcare Technology & Innovation UCITS ETF USD AccIE00BK5BC677 | 133 | 0.49% p.a. | Accumulating | Ireland | Full replication | |
| Invesco MSCI China Technology All Shares Stock Connect UCITS ETF AccIE00BM8QS095 | 118 | 0.49% p.a. | Accumulating | Ireland | Full replication | |
| HANetf HAN-GINS Tech Megatrend Equal Weight UCITS ETFIE00BDDRF700 | 85 | 0.59% p.a. | Accumulating | Ireland | Full replication | |
| ARK Genomic Revolution UCITS ETF USD AccumulatingIE000O5M6XO1 | 36 | 0.75% p.a. | Accumulating | Ireland | Full replication | |
| Invesco ChiNext 50 UCITS ETF AccIE000AWRDWI7 | 31 | 0.49% p.a. | Accumulating | Ireland | Full replication | |
| Amundi MSCI China Tech UCITS ETF USD AccLU1681044050 | 31 | 0.55% p.a. | Accumulating | Luxembourg | Full replication | |
| WisdomTree Megatrends UCITS ETF USDIE0000902GT6 | 26 | 0.50% p.a. | Accumulating | Ireland | Full replication | |
| Xtrackers Harvest MSCI China Tech 100 UCITS ETF 1C 1CLU2376679564 | 22 | 0.44% p.a. | Accumulating | Luxembourg | Full replication | |
| Xtrackers World Small Cap Green Tech Innovators UCITS ETF 1CLU2859297330 | 20 | 0.45% p.a. | Accumulating | Luxembourg | Full replication | |
| L&G Pharma Breakthrough UCITS ETFIE00BF0H7608 | 15 | 0.49% p.a. | Accumulating | Ireland | Full replication | |
| Harbor Health Care UCITS ETF AccumulatingIE00BJQTJ848 | 12 | 0.89% p.a. | Accumulating | Ireland | Full replication | |
| VanEck Genomics and Healthcare Innovators UCITS ETF AIE000B9PQW54 | 11 | 0.35% p.a. | Accumulating | Ireland | Full replication | |
| Xtrackers World Green Tech Innovators UCITS ETF 1CLU2859392081 | 11 | 0.35% p.a. | Accumulating | Luxembourg | Full replication | |
| Xtrackers MSCI Innovation UCITS ETF 1C 1CIE0006FFX5U1 | 6 | 0.30% p.a. | Accumulating | Ireland | Full replication | |
| First Trust Indxx NextG UCITS ETF AccIE00BWTNM743 | 6 | 0.70% p.a. | Accumulating | Ireland | Full replication | |
| Xtrackers MSCI Genomic Healthcare Innovation UCITS ETF 1C 1CIE000KD0BZ68 | 6 | 0.30% p.a. | Accumulating | Ireland | Full replication | |
| KraneShares ICBCUBS SSE STAR Market 50 Index UCITS ETF IE00BKPJY434 | 5 | 0.82% p.a. | Accumulating | Ireland | Full replication | |
| Janus Henderson US Transformational Growth High Conviction Equity UCITS ETF USD Acc.IE0009ZTL4B5 | 4 | 0.49% p.a. | Accumulating | Ireland | Full replication | |
| First Trust Alerian Disruptive Technology Real Estate UCITS ETF AccIE000RN036E0 | 0 | 0.60% p.a. | Accumulating | Ireland | Full replication | |
| First Trust Alerian Disruptive Technology Real Estate UCITS ETF DistIE000C75IMX8 | 0 | 0.60% p.a. | Distributing | Ireland | Full replication |
Source: justETF.com; As of 07/12/2025
Return comparison of all innovation ETFs
The table shows the returns of all innovation ETFs in comparison. All return figures are including dividends as of month end. Besides the return the reference date on which you conduct the comparison is important. In order to find the best ETFs, you can also perform a chart comparison.
Source: justETF.com; As of 30/11/2025; Calculations in GBP including dividends