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The best Innovation ETFs

How to invest in innovative technologies using ETFs

0,18% p.a. - 0,89% p.a.
annual total expense ratio (TER) of innovation ETFs
24 Indices
on innovative technologies, which are tracked by ETFs
25 ETFs
on innovative technologies
 
The best indices for innovation ETFs

How do I invest in innovative technologies?

Gaining new insights through research and using these insights to develop and implement new technologies is part of the business model of many companies.

Many of these efforts, with particular economic impact and dissemination, are expected to be in the health sector. The same applies to digital technologies, whose effects will probably not result in evolution but in a complete transformation of value chains and sales processes. Index providers evaluate companies according to their ambitions for innovation and construct specific indices based on this information.

In this investment guide, you will find all ETFs that allow you to invest in innovative technologies. Currently, there are 25 ETFs available.
 

iSTOXX® FactSet Breakthrough Healthcare performance

1 month: -0,40%
1 year: 12,59%
3 years: 6,92%
5 years: -6,31%
 

Innovation ETFs in comparison

The most important factors at a glance

When choosing an innovation ETF one should consider several other factors in addition to the methodology of the underlying index and performance of an ETF. For better comparison, you will find a list of all innovation ETFs with details on size, cost, age, income, domicile and replication method ranked by fund size.

Compare all innovation ETFs in detail
Compare all innovation ETFs in a chart

ETF name
ISIN		   Fund size
in m EUR		 TER
in %		 Use of profits Fund domicile Replication method
iShares Healthcare Innovation UCITS ETFIE00BYZK4776 834 0,40% p.a. Accumulerend Ierland Geoptimaliseerde sampling
ARK Innovation UCITS ETF USD AccumulatingIE000GA3D489 271 0,75% p.a. Accumulerend Ierland Volledige replicatie
Amundi MSCI China Tech UCITS ETF EUR AccLU1681043912 256 0,55% p.a. Accumulerend Luxemburg Volledige replicatie
UBS Solactive China Technology UCITS ETF USD accLU2265794276 232 0,47% p.a. Accumulerend Luxemburg Volledige replicatie
UBS Solactive China Technology UCITS ETF hEUR accLU2265794946 170 0,50% p.a. Accumulerend Luxemburg Volledige replicatie
L&G Healthcare Technology & Innovation UCITS ETF USD AccIE00BK5BC677 157 0,49% p.a. Accumulerend Ierland Volledige replicatie
Amundi MSCI Disruptive Technology UCITS ETF AccLU2023678282 151 0,45% p.a. Accumulerend Luxemburg Volledige replicatie
Invesco MSCI China Technology All Shares Stock Connect UCITS ETF AccIE00BM8QS095 136 0,49% p.a. Accumulerend Ierland Volledige replicatie
Invesco ChiNext 50 UCITS ETF AccIE000AWRDWI7 97 0,49% p.a. Accumulerend Ierland Volledige replicatie
HANetf HAN-GINS Tech Megatrend Equal Weight UCITS ETFIE00BDDRF700 92 0,59% p.a. Accumulerend Ierland Volledige replicatie
Xtrackers World Small Cap Green Tech Innovators UCITS ETF 1CLU2859297330 63 0,45% p.a. Accumulerend Luxemburg Volledige replicatie
WisdomTree Megatrends UCITS ETF USDIE0000902GT6 49 0,50% p.a. Accumulerend Ierland Volledige replicatie
ARK Genomic Revolution UCITS ETF USD AccumulatingIE000O5M6XO1 45 0,75% p.a. Accumulerend Ierland Volledige replicatie
UBS MSCI USA Tech 125 Universal UCITS ETF USD accIE0003B4BV34 35 0,18% p.a. Accumulerend Ierland Volledige replicatie
Xtrackers Harvest MSCI China Tech 100 UCITS ETF 1CLU2376679564 34 0,44% p.a. Accumulerend Luxemburg Volledige replicatie
Amundi MSCI China Tech UCITS ETF USD AccLU1681044050 19 0,55% p.a. Accumulerend Luxemburg Volledige replicatie
L&G Pharma Breakthrough UCITS ETFIE00BF0H7608 16 0,49% p.a. Accumulerend Ierland Volledige replicatie
Xtrackers World Green Tech Innovators UCITS ETF 1CLU2859392081 15 0,35% p.a. Accumulerend Luxemburg Volledige replicatie
Harbor Health Care UCITS ETF AccumulatingIE00BJQTJ848 12 0,89% p.a. Accumulerend Ierland Volledige replicatie
VanEck Genomics and Healthcare Innovators UCITS ETF AIE000B9PQW54 11 0,35% p.a. Accumulerend Ierland Volledige replicatie
First Trust Indxx NextG UCITS ETF AccIE00BWTNM743 8 0,70% p.a. Accumulerend Ierland Volledige replicatie
Xtrackers MSCI Genomic Healthcare Innovation UCITS ETF 1CIE000KD0BZ68 7 0,30% p.a. Accumulerend Ierland Volledige replicatie
WisdomTree Tech Megatrends UCITS ETF USD AccIE0007Z28IJ7 6 0,50% p.a. Accumulerend Ierland Geoptimaliseerde sampling
Xtrackers MSCI Innovation UCITS ETF 1CIE0006FFX5U1 6 0,30% p.a. Accumulerend Ierland Volledige replicatie
First Trust Alerian Disruptive Technology Real Estate UCITS ETF AccIE000RN036E0 1 0,60% p.a. Accumulerend Ierland Volledige replicatie

Source: justETF.com; As of 12-05-2026

 

Find the best Innovation ETF

Return comparison of all innovation ETFs

The table shows the returns of all innovation ETFs in comparison. All return figures are including dividends as of month end. Besides the return the reference date on which you conduct the comparison is important. In order to find the best ETFs, you can also perform a chart comparison.

ETF   1 month
in %		 3 months
in %		 6 months
in %		 1 year
in %		 3 years
in %
Invesco ChiNext 50 UCITS ETF Acc 13,34% 11,47% 16,88% 116,49% -
WisdomTree Megatrends UCITS ETF USD 16,08% 8,82% 9,96% 54,35% -
First Trust Indxx NextG UCITS ETF Acc 20,59% 20,38% 21,18% 52,09% 94,30%
ARK Innovation UCITS ETF USD Accumulating 19,15% 4,65% -9,36% 51,85% -
UBS MSCI USA Tech 125 Universal UCITS ETF USD acc 17,77% 7,30% 0,57% 37,31% -
ARK Genomic Revolution UCITS ETF USD Accumulating 18,92% 1,04% 0,83% 34,07% -
Xtrackers World Small Cap Green Tech Innovators UCITS ETF 1C 9,36% 3,32% 6,43% 33,42% -
HANetf HAN-GINS Tech Megatrend Equal Weight UCITS ETF 18,34% 5,09% -3,74% 32,77% 68,24%
Amundi MSCI China Tech UCITS ETF USD Acc 4,52% -1,37% -8,58% 31,26% 8,97%
Amundi MSCI China Tech UCITS ETF EUR Acc 4,10% -1,79% -8,70% 30,88% 9,29%
Amundi MSCI Disruptive Technology UCITS ETF Acc 18,38% 8,94% 1,13% 30,51% 58,76%
L&G Pharma Breakthrough UCITS ETF 4,06% 2,70% 3,87% 26,47% 11,74%
Xtrackers Harvest MSCI China Tech 100 UCITS ETF 1C 6,48% 0,10% -6,18% 24,75% 28,06%
Xtrackers World Green Tech Innovators UCITS ETF 1C 9,98% 3,49% 2,02% 24,36% -
L&G Healthcare Technology & Innovation UCITS ETF USD Acc 2,93% -7,30% 0,00% 21,12% 5,11%
Xtrackers MSCI Genomic Healthcare Innovation UCITS ETF 1C 0,18% -7,17% -4,42% 15,14% -0,65%
Invesco MSCI China Technology All Shares Stock Connect UCITS ETF Acc 5,03% -2,39% -10,00% 14,95% 25,90%
Xtrackers MSCI Innovation UCITS ETF 1C 10,36% -0,12% -5,14% 13,33% 48,76%
iShares Healthcare Innovation UCITS ETF -0,14% -6,27% -0,81% 12,42% 7,95%
UBS Solactive China Technology UCITS ETF hEUR acc 3,52% -9,91% -16,03% 8,99% 30,38%
First Trust Alerian Disruptive Technology Real Estate UCITS ETF Acc 8,68% 7,99% 6,70% 8,18% 6,28%
Harbor Health Care UCITS ETF Accumulating 4,93% -3,18% -5,89% 7,94% -7,12%
UBS Solactive China Technology UCITS ETF USD acc 1,37% -8,38% -17,04% 6,38% 27,05%
VanEck Genomics and Healthcare Innovators UCITS ETF A 0,24% -10,94% -11,41% 5,94% -11,31%
WisdomTree Tech Megatrends UCITS ETF USD Acc 17,59% - - - -
ETF   2026
in %		 2025
in %		 2024
in %		 2023
in %		 2022
in %
First Trust Indxx NextG UCITS ETF Acc 24,27% 13,37% 19,82% 23,29% -19,74%
Invesco ChiNext 50 UCITS ETF Acc 17,29% 52,50% - - -
WisdomTree Megatrends UCITS ETF USD 15,82% 15,24% 9,96% - -
First Trust Alerian Disruptive Technology Real Estate UCITS ETF Acc 8,61% -5,83% -4,18% 9,24% -
Amundi MSCI Disruptive Technology UCITS ETF Acc 6,68% 8,10% 20,71% 19,39% -30,75%
HANetf HAN-GINS Tech Megatrend Equal Weight UCITS ETF 6,09% 5,31% 22,50% 40,67% -41,42%
Xtrackers World Small Cap Green Tech Innovators UCITS ETF 1C 5,11% 15,01% - - -
UBS MSCI USA Tech 125 Universal UCITS ETF USD acc 4,57% 6,70% - - -
ARK Genomic Revolution UCITS ETF USD Accumulating 4,09% 9,22% - - -
Xtrackers World Green Tech Innovators UCITS ETF 1C 2,39% 7,35% - - -
L&G Pharma Breakthrough UCITS ETF 1,81% 20,92% 1,37% -13,42% -1,53%
Xtrackers Harvest MSCI China Tech 100 UCITS ETF 1C 0,87% 17,97% 22,19% -18,13% -
Amundi MSCI China Tech UCITS ETF USD Acc 0,86% 22,55% 8,38% -14,25% -3,27%
Amundi MSCI China Tech UCITS ETF EUR Acc 0,08% 22,21% 8,70% -14,17% -2,93%
ARK Innovation UCITS ETF USD Accumulating -0,43% 22,58% - - -
Invesco MSCI China Technology All Shares Stock Connect UCITS ETF Acc -1,30% 16,88% 27,98% -21,40% -26,43%
Xtrackers MSCI Innovation UCITS ETF 1C -3,00% 1,39% 29,60% 27,60% -
iShares Healthcare Innovation UCITS ETF -4,93% 4,79% 7,98% -1,46% -18,99%
Harbor Health Care UCITS ETF Accumulating -5,75% 5,94% -3,47% -1,92% -25,63%
L&G Healthcare Technology & Innovation UCITS ETF USD Acc -6,28% 9,92% 9,53% -6,26% -29,18%
UBS Solactive China Technology UCITS ETF hEUR acc -7,49% 40,64% 9,30% -12,24% -34,40%
UBS Solactive China Technology UCITS ETF USD acc -7,49% 24,91% 18,01% -13,60% -27,68%
Xtrackers MSCI Genomic Healthcare Innovation UCITS ETF 1C -7,88% 5,48% 3,95% -7,06% -
VanEck Genomics and Healthcare Innovators UCITS ETF A -12,14% 4,06% 0,89% -8,09% -
WisdomTree Tech Megatrends UCITS ETF USD Acc - - - - -

Source: justETF.com; As of 30-04-2026; Calculations in EUR including dividends