The best Innovation ETFs

How to invest in innovative technologies using ETFs

0.18% p.a. - 0.89% p.a.
annual total expense ratio (TER) of innovation ETFs
on innovative technologies, which are tracked by ETFs
on innovative technologies
 
The best indices for innovation ETFs

How do I invest in innovative technologies?

Gaining new insights through research and using these insights to develop and implement new technologies is part of the business model of many companies.

Many of these efforts, with particular economic impact and dissemination, are expected to be in the health sector. The same applies to digital technologies, whose effects will probably not result in evolution but in a complete transformation of value chains and sales processes. Index providers evaluate companies according to their ambitions for innovation and construct specific indices based on this information.

In this investment guide, you will find all ETFs that allow you to invest in innovative technologies. Currently, there are 28 ETFs available.
 

iSTOXX® FactSet Breakthrough Healthcare performance

1 month: 4.98%
1 year: 29.39%
3 years: 34.91%
5 years: 2.67%
 

Innovation ETFs in comparison

The most important factors at a glance

When choosing an innovation ETF one should consider several other factors in addition to the methodology of the underlying index and performance of an ETF. For better comparison, you will find a list of all innovation ETFs with details on size, cost, age, income, domicile and replication method ranked by fund size.

Compare all innovation ETFs in detail
Compare all innovation ETFs in a chart

ETF name
ISIN
  Fund size
in m EUR
TER
in %
Use of profits Fund domicile Replication method
iShares Healthcare Innovation UCITS ETFIE00BYZK4776 1,080 0.40% p.a. Accumulating Ireland Optimized sampling
ARK Innovation UCITS ETF USD AccumulatingIE000GA3D489 263 0.75% p.a. Accumulating Ireland Full replication
L&G Healthcare Technology & Innovation UCITS ETF USD AccIE00BK5BC677 261 0.49% p.a. Accumulating Ireland Full replication
Invesco ChiNext 50 UCITS ETF IE000AWRDWI7 228 0.49% p.a. Accumulating Ireland Full replication
UBS Solactive China Technology UCITS ETF USD accLU2265794276 219 0.47% p.a. Accumulating Luxembourg Full replication
Amundi MSCI China Tech UCITS ETF EURLU1681043912 201 0.55% p.a. Accumulating Luxembourg Full replication
Invesco MSCI China Technology All Shares Stock Connect UCITS ETF IE00BM8QS095 134 0.49% p.a. Accumulating Ireland Full replication
UBS Solactive China Technology UCITS ETF hEUR accLU2265794946 108 0.50% p.a. Accumulating Luxembourg Full replication
HANetf HAN-GINS Tech Megatrend Equal Weight UCITS ETFIE00BDDRF700 100 0.59% p.a. Accumulating Ireland Full replication
Xtrackers World Small Cap Green Tech Innovators UCITS ETF 1CLU2859297330 76 0.45% p.a. Accumulating Luxembourg Full replication
ARK Genomic Revolution UCITS ETF USD AccumulatingIE000O5M6XO1 76 0.75% p.a. Accumulating Ireland Full replication
WisdomTree Megatrends UCITS ETF USDIE0000902GT6 59 0.50% p.a. Accumulating Ireland Full replication
Xtrackers Harvest MSCI China Tech 100 UCITS ETF 1CLU2376679564 43 0.44% p.a. Accumulating Luxembourg Full replication
Amundi MSCI China Tech UCITS ETF USDLU1681044050 37 0.55% p.a. Accumulating Luxembourg Full replication
KraneShares ICBCUBS China Technology & Semiconductor STAR 50 Index UCITS ETF USDIE00BKPJY434 33 0.82% p.a. Accumulating Ireland Full replication
UBS MSCI USA Tech 125 Universal UCITS ETF USD accIE0003B4BV34 32 0.18% p.a. Accumulating Ireland Full replication
L&G Pharma Breakthrough UCITS ETFIE00BF0H7608 20 0.49% p.a. Accumulating Ireland Full replication
Xtrackers World Green Tech Innovators UCITS ETF 1CLU2859392081 16 0.35% p.a. Accumulating Luxembourg Full replication
Harbor Health Care UCITS ETF AccumulatingIE00BJQTJ848 13 0.89% p.a. Accumulating Ireland Full replication
VanEck Genomics and Healthcare Innovators UCITS ETF AIE000B9PQW54 13 0.35% p.a. Accumulating Ireland Full replication
Xtrackers MSCI Genomic Healthcare Innovation UCITS ETF 1CIE000KD0BZ68 9 0.25% p.a. Accumulating Ireland Full replication
First Trust Indxx NextG UCITS ETF AccIE00BWTNM743 8 0.70% p.a. Accumulating Ireland Full replication
Xtrackers MSCI Innovation UCITS ETF 1CIE0006FFX5U1 6 0.25% p.a. Accumulating Ireland Full replication
AB Global Disruptors Portfolio UCITS ETF USD AccLU3322522163 5 0.78% p.a. Accumulating Luxembourg Full replication
WisdomTree Tech Megatrends UCITS ETF USD AccIE0007Z28IJ7 4 0.50% p.a. Accumulating Ireland Optimized sampling
Janus Henderson US Transformational Growth High Conviction Equity UCITS ETF USD Acc.IE0009ZTL4B5 3 0.49% p.a. Accumulating Ireland Full replication
First Trust Alerian Disruptive Technology Real Estate UCITS ETF AccIE000RN036E0 1 0.60% p.a. Accumulating Ireland Full replication
BIT Global Technology Leaders UCITS ETFDE000A4231H9 0 0.46% p.a. Accumulating Germany Full replication

Source: justETF.com; As of 17.08.26

 

Return comparison of all innovation ETFs

The table shows the returns of all innovation ETFs in comparison. All return figures are including dividends as of month end. Besides the return the reference date on which you conduct the comparison is important. In order to find the best ETFs, you can also perform a chart comparison.

ETF   1 month
in %
3 months
in %
6 months
in %
1 year
in %
3 years
in %
KraneShares ICBCUBS China Technology & Semiconductor STAR 50 Index UCITS ETF USD -26.57% 6.93% 15.93% 63.46% 56.94%
Invesco ChiNext 50 UCITS ETF -26.34% -7.91% 2.65% 60.24% -
ARK Genomic Revolution UCITS ETF USD Accumulating -9.93% 29.34% 30.69% 60.10% -
First Trust Indxx NextG UCITS ETF Acc -5.22% 10.95% 33.56% 51.83% 100.09%
L&G Healthcare Technology & Innovation UCITS ETF USD Acc 2.04% 17.52% 8.94% 38.26% 22.23%
Xtrackers World Small Cap Green Tech Innovators UCITS ETF 1C -2.11% 8.88% 12.49% 33.76% -
Xtrackers MSCI Genomic Healthcare Innovation UCITS ETF 1C -1.57% 18.35% 9.87% 28.92% 15.49%
L&G Pharma Breakthrough UCITS ETF -5.80% 4.66% 7.48% 26.15% 21.92%
iShares Healthcare Innovation UCITS ETF 0.12% 15.01% 7.80% 25.63% 21.29%
WisdomTree Megatrends UCITS ETF USD -12.05% -6.99% 1.21% 22.89% -
UBS MSCI USA Tech 125 Universal UCITS ETF USD acc -1.17% 5.67% 13.39% 18.51% -
Xtrackers World Green Tech Innovators UCITS ETF 1C 0.03% 6.80% 10.53% 16.93% -
Janus Henderson US Transformational Growth High Conviction Equity UCITS ETF USD Acc. -7.69% 6.64% 17.31% 14.75% -
Harbor Health Care UCITS ETF Accumulating -5.06% 8.61% 5.15% 13.21% -1.98%
First Trust Alerian Disruptive Technology Real Estate UCITS ETF Acc 3.12% 3.83% 12.13% 13.04% 7.37%
HANetf HAN-GINS Tech Megatrend Equal Weight UCITS ETF -8.40% 2.17% 7.37% 12.66% 40.65%
Xtrackers MSCI Innovation UCITS ETF 1C -0.34% 9.51% 9.38% 11.21% 41.34%
VanEck Genomics and Healthcare Innovators UCITS ETF A -1.46% 15.77% 3.10% 10.48% 1.29%
Xtrackers Harvest MSCI China Tech 100 UCITS ETF 1C -5.21% -3.28% -3.19% 9.92% 14.56%
Amundi MSCI China Tech UCITS ETF USD -3.10% -5.76% -7.05% 9.23% -1.39%
Amundi MSCI China Tech UCITS ETF EUR -2.94% -5.70% -7.39% 9.03% -1.54%
Invesco MSCI China Technology All Shares Stock Connect UCITS ETF -3.46% -2.16% -4.49% 5.39% 13.33%
ARK Innovation UCITS ETF USD Accumulating -12.48% -1.43% 3.15% 0.44% -
UBS Solactive China Technology UCITS ETF USD acc 0.16% -3.90% -11.95% -9.85% 9.01%
UBS Solactive China Technology UCITS ETF hEUR acc 0.69% -6.15% -15.45% -11.31% 10.69%
AB Global Disruptors Portfolio UCITS ETF USD Acc -15.03% - - - -
BIT Global Technology Leaders UCITS ETF - - - - -
WisdomTree Tech Megatrends UCITS ETF USD Acc -12.08% 2.79% - - -
ETF   2026
in %
2025
in %
2024
in %
2023
in %
2022
in %
First Trust Indxx NextG UCITS ETF Acc 37.88% 13.37% 19.82% 23.29% -19.74%
ARK Genomic Revolution UCITS ETF USD Accumulating 34.62% 9.22% - - -
KraneShares ICBCUBS China Technology & Semiconductor STAR 50 Index UCITS ETF USD 15.38% 25.30% 12.30% -21.03% -34.49%
Xtrackers World Small Cap Green Tech Innovators UCITS ETF 1C 14.44% 15.01% - - -
First Trust Alerian Disruptive Technology Real Estate UCITS ETF Acc 12.77% -5.83% -4.18% 9.24% -
UBS MSCI USA Tech 125 Universal UCITS ETF USD acc 10.50% 6.70% - - -
L&G Healthcare Technology & Innovation UCITS ETF USD Acc 10.13% 9.92% 9.53% -6.26% -29.18%
Janus Henderson US Transformational Growth High Conviction Equity UCITS ETF USD Acc. 9.69% - - - -
Xtrackers World Green Tech Innovators UCITS ETF 1C 9.35% 7.35% - - -
iShares Healthcare Innovation UCITS ETF 9.34% 4.79% 7.98% -1.46% -18.99%
Xtrackers MSCI Genomic Healthcare Innovation UCITS ETF 1C 9.02% 5.48% 3.95% -7.06% -
HANetf HAN-GINS Tech Megatrend Equal Weight UCITS ETF 8.39% 5.31% 22.50% 40.67% -41.42%
Invesco ChiNext 50 UCITS ETF 8.00% 52.50% - - -
WisdomTree Megatrends UCITS ETF USD 7.72% 15.24% 9.96% - -
L&G Pharma Breakthrough UCITS ETF 6.56% 20.92% 1.37% -13.42% -1.53%
Xtrackers MSCI Innovation UCITS ETF 1C 6.22% 1.39% 29.60% 27.60% -
Harbor Health Care UCITS ETF Accumulating 2.36% 5.94% -3.47% -1.92% -25.63%
VanEck Genomics and Healthcare Innovators UCITS ETF A 1.71% 4.06% 0.89% -8.09% -
ARK Innovation UCITS ETF USD Accumulating -1.86% 22.58% - - -
Xtrackers Harvest MSCI China Tech 100 UCITS ETF 1C -2.44% 17.97% 22.19% -18.13% -
Invesco MSCI China Technology All Shares Stock Connect UCITS ETF -3.43% 16.88% 27.98% -21.40% -26.43%
Amundi MSCI China Tech UCITS ETF USD -4.95% 22.55% 8.38% -14.25% -3.27%
Amundi MSCI China Tech UCITS ETF EUR -5.62% 22.21% 8.70% -14.17% -2.93%
UBS Solactive China Technology UCITS ETF USD acc -11.10% 24.91% 18.01% -13.60% -27.68%
UBS Solactive China Technology UCITS ETF hEUR acc -13.17% 40.64% 9.30% -12.24% -34.40%
AB Global Disruptors Portfolio UCITS ETF USD Acc - - - - -
BIT Global Technology Leaders UCITS ETF - - - - -
WisdomTree Tech Megatrends UCITS ETF USD Acc - - - - -

Source: justETF.com; As of 31.07.26; Calculations in EUR including dividends